Fig. 5

The effect of HFD on TAD and PEI changes in mouse liver tissues. The study investigated the determination of enhancer quantity and their effects on gene expression in mouse liver tissues under two conditions: normal (A) and high-fat diet (HFD) (B). Additionally, the examination of RPS value and its correlation with gene expression was carried out in mice's normal (C) and HFD (D) liver tissues. Moreover, identifying shared and distinct TAD boundaries (E) and exploring PEI (F) were conducted in normal and HFD mouse liver tissues. G Gene functional analysis of goose-specific genes