Fig. 4

eGWAS of SERPINB6 expression and effects of different genotypes of rs317934171. A and B Manhattan plots and quantile‒quantile (Q‒Q) plots of eQTLs for SERPINB6. Each dot represents a SNP. The horizontal red and blue lines indicate the genome-wide significant (P = 5.12 × 10^–9) and suggestive (P = 1.02 × 10^–7) thresholds, respectively. C Venn diagram of 3 overlapping SNPs (rs317934171, rs14200392 and rs731580755) based on the GLM and eGWAS. GLM: general linear model, eGWAS: expression genome-wide association study. D and E Differences in the EW and BMW between different genotypes of rs317934171. ns: P > 0.05, **: P < 0.01, BMW: breast muscle weight, EW: eviscerated weight. F Differences in the SERPINB6 expression level between different genotypes of rs317934171. ns: P > 0.05, **: P < 0.01, ***: P < 0.001, ****: P < 0.0001