Fig. 2
From: Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid
Principal component analysis (PCA), heatmap, and miRNA expression profiles. Small-RNA sequence data and miRNA expression profile overviews. A Principal component analysis. B Heatmap and hierarchical clustering of expressed miRNAs. Red and green colors represent high and low expressed miRNAs, respectively. C miRNA expression profiles in each seasonal group. Experimental groups are represented as SAN (Spring Anovulatory), SOV (Spring Ovulatory), SUM (Summer), and FOV (Fall Ovulatory) seasons. EVs and miRNAs were obtained from four independent samples, harboring different suffices (1, 2, 3, or 4) in each group. In the FOV group, however, FOV_1 was removed from further analyses (Fig. 2B and 2C) due to similarity to the SAN group (PCA analysis)