Fig. 7

The DRP1 inhibitor Mdivi-1 suppresses excessive mitochondrial fission and mitochondria-dependent apoptosis. A The effects of Mdivi-1 on the expression of proteins associated with mitochondrial dynamics. B Quantification of mitochondrial-related protein expression. C and D Analysis of SC apoptosis using flow cytometry. E Effects of Mdivi-1 pretreatment on the expression of mitochondria-dependent apoptotic proteins. F Quantification of mitochondria-dependent apoptotic proteins. *P < 0.05, **P < 0.01 vs. control; # P < 0.05 vs. HS