Fig. 6

The potential regulatory variants of immune core genes are enriched in QTLs of porcine complex traits and significantly correlated with immune pathway activity score. A Bar chart of the enrichment ratio of SNPs within a ±100 kb region surrounding the immune core genes with the QTL data of five pig phenotypes. The numerator represents the number of QTLs significantly enriched with SNPs, and the denominator represents the total number of QTLs. B Potential regulatory SNP (6_134641947) in IFI44 gene body region. The position of the SNP has peaks of H3K4me1 and H3K27ac. Individuals with the T genotype show higher gene expression (P = 0.069). C The potential regulatory SNP (6_134641947) of IFI44 was significantly associated with multiple immune pathway activity score, and individuals with T genotype show higher activity scores