Fig. 5
From: Florfenicol-induced dysbiosis impairs intestinal homeostasis and host immune system in laying hens
Butyrate administration in chickens with dysbiosis restores hypoxic conditions and mitigates gut permeability. A Prior to and throughout florfenicol administration, the chickens (n = 6) were supplied with butyrate in their drinking water. B Restoration of cecal butyrate was examined using HPLC. Following butyrate treatment, genomic changes related to hypoxia (C and D), hypoxic conditions (scale bar = 100 µm) (E), genomic changes related to intestinal barrier function (F and G), and changes in gut permeability (H) were examined. FFC, florfenicol. FFC + B, florfenicol + butyrate. Results are presented as the mean ± SEM. Statistical differences were determined in a Tukey test; *P < 0.05, **P < 0.01, ***P < 0.001