Fig. 2

High throughput screening of amino acids and their metabolites. A and B Z-scores of 85 amino acid metabolites following a primary screening. C and D Time-dependent response of pTr-CDX2/luc-TEAD4/Rluc to three screened nutrients. E–H Impact of selected amino acid metabolites on early embryonic development-related genes. Data were presented as means ± SEM. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001